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Archive : Applied Mathematics and Mathematical Medicine and Biology Seminar

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Chad Giusti, Mathematical Sciences, UDChad Giusti, Mathematical Sciences, UDEWG 336Title: Topological methods in biology (and elsewhere) Abstract: In the last twenty years, applications of algebraic topology to the sciences have grown dramatically in both number and sophistication. This growth has been driven by the increasing need for new techniques for understanding qualitative features of massive, noisy, and often incomplete data sets, and has begun to provide insights into a range of problems that have proven difficult to approach with more standard methods. In this talk, we will survey the basic techniques and current state of affairs in applied topology, then look more closely at recent applications in the analysis of biomolecules and coding properties of neural systems.9/13/2017 6:30:00 PM9/13/2017 7:20:00 PMFalse
William WeintraubWilliam WeintraubEWG 336Title: Hypertension: #1 Modifiable risk factor for cardiovascular disease worldwide Abstract: Hypertension is often called the silent killer. However, it is actually the #1 modifiable risk factor for cardiovascular disease worldwide. In this talk the epidemiology of hypertension will be reviewed, including assessment of risk in the developed and developing world. Key clinical trials will be reviewed. The importance of intensive treatment will be reviewed by examination of the SPRINT trial. Cost-effectiveness of hypertension control will also be addressed.9/6/2017 6:30:00 PM9/6/2017 7:20:00 PMFalse
Simon Garnier, NJITSimon Garnier, NJITEWG 336<div>Title: Living Architectures in New World Army Ants </div> <br> <div>Abstract: One of the most spectacular examples of construction by social insects are the self-assembling structures formed by New World army ants. In order to conquer the complex terrain of the tropical forests of Central and South America, these nomadic ants create temporary support structures with their own bodies – bridges, pothole covers, and buttresses – forming the backbone of dynamical ant “superhighways”. In particular, bridges formed by the army ants can self-assemble across a wide variety of environments and spanning conditions, and have been shown to recover from damage, adapt their size according to traffic, and even spontaneously disassemble when under-used. The army ants’ living architectures are an existence proof of how complex and dynamical biological structures can be achieved from the cooperation of large numbers of limited individuals. </div> <div> Over the last few years, such natural systems have inspired the development of a new kind of robotics, where simple, independent agents act together to build large-scale structures as needed, guided only by their reactions to the local situations they encounter. Large robotic swarms that could self-assemble could accomplish remarkable tasks, such as creating bridges to navigate complex terrain, plugs to repair structural breaches, or supports to stabilize a failing structure. Nevertheless, how to achieve complex artificial self-assemblages remains poorly understood. During this talk I will review our latest discoveries on - and current investigations in - the mechanisms of construction in New World army ants, with the goal to provide insight into achieving successful self-assembly in artificial systems. </div>5/16/2017 6:00:00 PM5/16/2017 7:00:00 PMFalse
Wenrui Hao, Penn State UniversityWenrui Hao, Penn State UniversityEWG 336Mathematical modeling for vascular diseases <br><br> Atherosclerosis, the leading cause of death in the United States, is a disease in which plaque builds up inside the arteries. Two concentrations of cholesterol in the blood, LDL and HDL, are commonly usedto predict the risk factor for plaque growth. In this talk, I will describe a new mathematical model that predicts the plaque formation by using the combined levels of LDL and HDL. The model is given by a system of partial differential equations within the plaque region with a free boundary. This model is used to explore some drugs of regression of plaque in mice, and suggest that such drugs may also slow plaque growth in humans. Some computational and mathematical questions inspired by this model will also be discussed. I will also mention briefly some related projects, abdominal aortic aneurysm (AAA) and red blood cell aggregation. 5/2/2017 6:00:00 PM5/2/2017 7:00:00 PMFalse

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